Human recombinant interferon beta (prokaryotic)
- Without methionine derivatives at N-terminus
- Purity 98%
- Lipopolysaccharide impurities – 1 IU per 100 mcg of the protein
- Proteins of producing strain – no more than 10 ng per 10 IU
- Bioactivity - 1 000 000 units per 25 mcg
Price: on request
Interferon-beta (IFN-beta) is a polypeptide, normally produced by fibroblasts, that has antiviral and antiproliferative effects. Binding of IFN-beta to its receptor induces a complex transcriptional response. In immune cells (the most likely target of IFN-beta's therapeutic effect in MS), IFN-beta reduces antigen presentation and T-cell proliferation, alters cytokine and matrix metalloproteinase (MMP) expression, and restores suppressor function. The technology of production proposed by the authors allows obtaining IFNγ and IFNβ quickly, inexpensively, in large quantities.